Letter – Diuretics in primary hypertension – Reloaded

Thiazide diuretics in hypertension

Authors: Ferreira R. The use of diuretics (and beta-blockers) to treat hypertension has known a dramatic decline since the early 1980’s through to the early 1990s with the introduction of ACE-inhibitors and calcium channel blockers. However, thiazide diuretics are still a first line option to treat arterial hypertension, due to their efficacy and cost-effectiveness profile. We have presented ma...

Diuretics for hypertension.

A67-year-old African-American woman was referred to a hypertension specialty clinic for refractory hypertension and intermittent hypokalemia. Evaluations for primary aldosteronism and renal artery stenosis were negative; plasma renin was low. She had been hypertensive for 15 years. Most recently, she had taken chlorthalidone 25 mg, amlodipine 5 mg, and metoprolol 50 mg twice daily. She was not ...

Potassium-Sparing Diuretics in Hypertension

The use of diuretics in hypertension.

612 P&T® • September 2003 • Vol. 28 No. 9 The information cited in this article is available free of charge to hospitals that participate in the PharmScope Insights program. The program specializes in helping hospital pharmacies target areas for performance improvement by providing benchmarks from a panel of 80 hospitals nationwide. For information about joining PharmScope Insights, a division ...

Actual Place of Diuretics in Hypertension

Despite the large number of available anti-hypertensive drugs, diuretics remained a cornerstone of hypertension treatment [1]. Indeed, they are the second most commonly prescribed class of antihypertensive medication. For instance, 12% of US adults were prescribed a diuretic, and the relative increase in prescriptions from 1999 through 2012 was 1.4 [2]. However, a question remains looking for a...